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Although the results of early studies were optimistic, with better than predicted outcomes in treated patients, a further case series was less promising

To minimize tirzepatide side effects, avoid or limit: Spicy foods Fatty foods, like processed meats, baked goods, fast food, and butter Alcohol Fizzy drinks Sugary foods and drinks Alliums, like garlic, leeks, and onions Keep a food and side effect diary to figure out your personal triggers

Interestingly, even in conditions of reduced GLP-1 secretion observed in individuals with obesity and T2D, its receptor-mediated effects remain intact